@@ -51,11 +51,10 @@ export const competitiveArray: PageContent[] = [
5151 title : "Competitive Binding" ,
5252 content : (
5353 < >
54- We now know the binding affinity of < A /> and < B /> . Our
55- competitive inhibitor, < D /> , also binds to < A /> and we want to
56- figure out how effective it is at blocking the binding of < B /> .
57- We cannot directly measure the formation of < AD /> (which is why
58- it's shown in grey).
54+ In the "High Affinity" section we determined the binding
55+ affinity of < A /> and < B /> . Our new competitive inhibitor,{ " " }
56+ < D /> , also binds to < A /> . Once it binds to < A /> , < B /> can no
57+ longer bind.
5958 </ >
6059 ) ,
6160 layout : LayoutType . LiveSimulation ,
@@ -64,54 +63,56 @@ export const competitiveArray: PageContent[] = [
6463 callToAction :
6564 "Press play and watch the how the two different complexes form over time." ,
6665 } ,
67-
6866 {
6967 title : "Start the experiment" ,
7068 content : (
7169 < >
72- Now, let's use this simulation to make measurements. We'll start
73- with [< D /> ] = 0 so we can get the formation of < AB /> without
74- any competition.
70+ We cannot directly measure the formation of < AD /> (which is why
71+ it's shown in grey). To figure out how strongly < B /> binds to{ " " }
72+ < A /> we're going to keep track of how adding more < D /> { " " }
73+ decreases the formation of < AB /> .
7574 </ >
7675 ) ,
76+ layout : LayoutType . LiveSimulation ,
77+ section : Section . Introduction ,
7778 actionButton : < StartExperiment /> ,
79+ progressionElement : START_EXPERIMENT_ID ,
7880 callToAction : (
7981 < >
8082 Click the < strong > Start experiment</ strong > button to reset the
8183 simulation and begin by pressing < strong > play</ strong > !
8284 </ >
8385 ) ,
84- section : Section . Introduction ,
85- layout : LayoutType . LiveSimulation ,
86- progressionElement : START_EXPERIMENT_ID ,
8786 } ,
8887 {
8988 title : "Start the experiment" ,
9089 content : (
9190 < >
92- Now, let's use this simulation to make measurements. We'll start
93- with [< D /> ] = 0 so we can get the formation of < AB /> without
94- any competition.
91+ We cannot directly measure the formation of < AD /> (which is why
92+ it's shown in grey). To figure out how strongly < B /> binds to{ " " }
93+ < A /> we're going to keep track of how adding more < D /> affects
94+ the amount of < AB /> formed.
9595 </ >
9696 ) ,
97+ layout : LayoutType . LiveSimulation ,
98+ section : Section . Introduction ,
9799 actionButton : < StartExperiment /> ,
100+ progressionElement : PLAY_BUTTON_ID ,
98101 callToAction : (
99102 < >
100103 Click the < strong > Start experiment</ strong > button to reset the
101104 simulation and begin by pressing < strong > play</ strong > !
102105 </ >
103106 ) ,
104- section : Section . Experiment ,
105- layout : LayoutType . LiveSimulation ,
106- progressionElement : PLAY_BUTTON_ID ,
107107 } ,
108+
108109 {
109110 title : "Find maximum complex formation" ,
110111 content : (
111112 < >
112- With [< D /> ] = 0, the < AB /> complex is able to form without any
113- inhibition. This will be our baseline for the max amount of { " " }
114- < AB /> that can form at these concentrations.{ " " }
113+ We are starting with [< D /> ] = 0, so the < AB /> complex is able
114+ to form without any inhibition. This will be our baseline for
115+ the max amount of < AB /> that can form at these concentrations.{ " " }
115116 </ >
116117 ) ,
117118 callToAction : (
@@ -130,7 +131,7 @@ export const competitiveArray: PageContent[] = [
130131 title : "Introduce the competitive inhibitor" ,
131132 content : (
132133 < >
133- Now let's see how the addition of < D /> affects the formation of{ " " }
134+ Now let's see how the addition of < D /> effects the formation of{ " " }
134135 < AB /> .
135136 </ >
136137 ) ,
@@ -151,10 +152,10 @@ export const competitiveArray: PageContent[] = [
151152 title : "Repeating the experiment" ,
152153 content : (
153154 < >
154- We want to understand the effect
155- < D /> has on the formation of < AB /> . Let’s repeat the
156- experiment with a new concentration of < D /> . We will keep the
157- concentration of < A /> and < B /> constant.
155+ We want to understand the affect < D /> has on the formation of { " " }
156+ < AB /> . Let’s repeat the experiment with a new concentration of { " " }
157+ < D /> . We will keep the concentration of < A /> and < B /> { " " }
158+ constant.
158159 </ >
159160 ) ,
160161 callToAction : (
@@ -175,8 +176,7 @@ export const competitiveArray: PageContent[] = [
175176 The constant K< sub > i</ sub > is analogous to K< sub > d</ sub > for
176177 inhibitors. K< sub > i</ sub > can be determined in this experiment
177178 by finding the IC< sub > 50</ sub > , the concentration of inhibitor
178- where the amount of
179- < AB /> complex is reduced by half.
179+ where the amount of < AB /> complex is reduced by half.
180180 </ >
181181 ) ,
182182 moreInfo : (
@@ -197,7 +197,7 @@ export const competitiveArray: PageContent[] = [
197197 } ,
198198 {
199199 content :
200- "Congratulations, you’ve completed the High Affinity experiment!" ,
200+ "Congratulations, you’ve completed the Competitive Binding experiment!" ,
201201 backButton : true ,
202202 // nextButton: true,
203203 nextButtonText : "View examples" ,
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