diff --git a/src/spatialdata_plot/pl/basic.py b/src/spatialdata_plot/pl/basic.py
index 38183fa8..e1d28d3b 100644
--- a/src/spatialdata_plot/pl/basic.py
+++ b/src/spatialdata_plot/pl/basic.py
@@ -293,7 +293,9 @@ def render_shapes(
         -----
         - Empty geometries will be removed at the time of plotting.
         - An `outline_width` of 0.0 leads to no border being plotted.
-        - When passing a color-like to 'color', this has precedence over the potential existence as a column name.
+        - If ``color`` is a string that is both a matplotlib color name and a column name in the
+          element or an annotating table, a ``ValueError`` is raised. Disambiguate by passing
+          a hex string (e.g. ``"#ffa500"``) or an RGB(A) tuple, or by renaming the column.
 
         Returns
         -------
diff --git a/src/spatialdata_plot/pl/utils.py b/src/spatialdata_plot/pl/utils.py
index 4e872c8f..dd0daee6 100644
--- a/src/spatialdata_plot/pl/utils.py
+++ b/src/spatialdata_plot/pl/utils.py
@@ -2280,6 +2280,41 @@ def _validate_show_parameters(
             )
 
 
+def _check_color_column_collision(
+    sdata: SpatialData,
+    elements: list[str],
+    color: str,
+    element_type: str,
+) -> None:
+    """Raise if ``color`` is a color-like string that also names a column in the element or its tables."""
+    matches: list[str] = []
+    for el in elements:
+        if element_type in {"shapes", "points"}:
+            try:
+                el_cols = sdata[el].columns
+            except (KeyError, AttributeError):
+                el_cols = ()
+            if color in el_cols:
+                matches.append(f"element '{el}'")
+                continue
+        try:
+            tables = get_element_annotators(sdata, el)
+        except (KeyError, ValueError):
+            tables = set()
+        for t in tables:
+            adata = sdata[t]
+            if color in adata.obs.columns or color in adata.var_names:
+                matches.append(f"table '{t}' (annotating '{el}')")
+                break
+    if matches:
+        locations = ", ".join(matches)
+        raise ValueError(
+            f"`color={color!r}` is ambiguous: it is a valid matplotlib color name AND a column "
+            f"name in {locations}. Disambiguate by either passing an unambiguous color form "
+            f"(hex string like '#ffa500' or an RGB(A) tuple), or by renaming the column."
+        )
+
+
 def _type_check_params(param_dict: dict[str, Any], element_type: str) -> dict[str, Any]:
     colorbar = param_dict.get("colorbar", "auto")
     if colorbar not in {True, False, None, "auto"}:
@@ -2330,7 +2365,8 @@ def _type_check_params(param_dict: dict[str, Any], element_type: str) -> dict[st
         if not isinstance(color, str | tuple | list):
             raise TypeError("Parameter 'color' must be a string or a tuple/list of floats.")
         if _is_color_like(color):
-            logger.info("Value for parameter 'color' appears to be a color, using it as such.")
+            if isinstance(color, str):
+                _check_color_column_collision(param_dict["sdata"], param_dict["element"], color, element_type)
             param_dict["col_for_color"] = None
             param_dict["color"] = Color(color)
             if param_dict["color"].alpha_is_user_defined():
diff --git a/tests/pl/test_utils.py b/tests/pl/test_utils.py
index a648b3d8..467a5efe 100644
--- a/tests/pl/test_utils.py
+++ b/tests/pl/test_utils.py
@@ -1,3 +1,4 @@
+import geopandas as gpd
 import matplotlib
 import matplotlib.pyplot as plt
 import numpy as np
@@ -5,7 +6,10 @@
 import pytest
 import scanpy as sc
 import xarray as xr
+from anndata import AnnData
+from shapely.geometry import Point
 from spatialdata import SpatialData
+from spatialdata.models import PointsModel, ShapesModel, TableModel
 
 import spatialdata_plot
 from spatialdata_plot.pl.render_params import Color
@@ -380,3 +384,39 @@ def test_exact_match_selects_that_scale(self):
         multiscale = self._make_multiscale((3, 500, 500), [2, 2])
         result = _multiscale_to_spatial_image(multiscale, dpi=100.0, width=2.5, height=2.5)
         assert result.sizes["x"] == 250
+
+
+def test_color_column_collision_on_element_columns_raises():
+    # regression test for #619, element-column path: points with an "orange" column + color="orange".
+    points = PointsModel.parse(pd.DataFrame({"x": [1.0, 2.0, 3.0], "y": [1.0, 2.0, 3.0], "orange": [0.1, 0.2, 0.3]}))
+    sdata = SpatialData(points={"pts": points})
+
+    with pytest.raises(ValueError, match=r"color='orange'.*ambiguous.*element 'pts'"):
+        sdata.pl.render_points("pts", color="orange")
+
+    sdata.pl.render_points("pts", color="#ffa500")
+    sdata.pl.render_points("pts", color=(1.0, 0.65, 0.0))
+
+
+def test_color_column_collision_on_annotating_table_raises():
+    # regression test for #619, table path: element has no "orange" column but its annotating table does.
+    shapes = ShapesModel.parse(gpd.GeoDataFrame({"geometry": [Point(i, 0) for i in range(3)], "radius": [0.5] * 3}))
+    obs = pd.DataFrame(
+        {
+            "region": pd.Categorical(["s"] * 3),
+            "instance_id": list(range(3)),
+            "orange": pd.Categorical(["A", "B", "A"]),
+        }
+    )
+    table = TableModel.parse(
+        AnnData(X=np.zeros((3, 1)), obs=obs),
+        region="s",
+        region_key="region",
+        instance_key="instance_id",
+    )
+    sdata = SpatialData(shapes={"s": shapes}, tables={"t": table})
+
+    with pytest.raises(ValueError, match=r"color='orange'.*ambiguous.*table 't'"):
+        sdata.pl.render_shapes("s", color="orange")
+
+    sdata.pl.render_shapes("s", color="#ffa500")