diff --git a/.cirun.yml b/.cirun.yml
new file mode 100644
index 0000000..263d0fa
--- /dev/null
+++ b/.cirun.yml
@@ -0,0 +1,11 @@
+runners:
+  - name: aws-gpu-runner
+    cloud: aws
+    instance_type: g4dn.xlarge
+    machine_image: ami-067a4ba2816407ee9
+    region: eu-north-1
+    preemptible:
+      - true
+      - false
+    labels:
+      - cirun-aws-gpu
diff --git a/.github/workflows/rsc_integration-test.yml b/.github/workflows/rsc_integration-test.yml
new file mode 100644
index 0000000..2740b5c
--- /dev/null
+++ b/.github/workflows/rsc_integration-test.yml
@@ -0,0 +1,115 @@
+name: Integration test RSC
+
+on:
+    schedule:
+      - cron: "0 0 * * *"  # Run daily at midnight UTC
+    push:
+      branches: [main]
+    pull_request:
+      branches: [main]
+
+concurrency:
+  group: ${{ github.workflow }}-${{ github.event.pull_request.number || github.ref }}
+  cancel-in-progress: true
+
+jobs:
+  test:
+    name: Integration test/ test (3.x rapids-singlecell)
+    runs-on: "cirun-aws-gpu--${{ github.run_id }}"
+    timeout-minutes: 30
+    outputs:
+      failure_type: ${{ steps.export_failure.outputs.failure_type }}
+
+    defaults:
+      run:
+        shell: bash -el {0}
+        working-directory: rapids_singlecell
+
+    env:
+      GH_TOKEN: ${{ secrets.TOKEN_FOR_ISSUE_WRITE }}
+
+    steps:
+      - name: Checkout this repository (integration-testing)
+        uses: actions/checkout@v4
+        with:
+          fetch-depth: 0
+
+      - name: Checkout rapids-singlecell
+        uses: actions/checkout@v4
+        with:
+          repository: scverse/rapids_singlecell
+          fetch-depth: 0
+          path: rapids_singlecell
+
+      - name: Nvidia SMI sanity check
+        run: nvidia-smi
+
+      - uses: mamba-org/setup-micromamba@v2
+        with:
+          environment-file: rapids_singlecell/ci/environment.yml
+          init-shell: >-
+            bash
+          post-cleanup: 'all'
+
+      - name: Install rapids-singlecell
+        id: install_pkg
+        run: >-
+          pip install -e .[test]
+          "scanpy @ git+https://github.com/scverse/scanpy.git"
+          "anndata @ git+https://github.com/scverse/anndata.git"
+
+      - name: Pip list
+        run: pip list
+
+      - name: Set failure type for install
+        if: failure()
+        run: |
+          echo "Installation failed for rapids-singlecell"
+          echo "failure_type=install" >> $GITHUB_ENV
+
+      - name: Run test
+        id: run_tests
+        run: pytest
+
+      - name: Set failure type for test
+        if: failure() && env.failure_type != 'install'
+        run: |
+          echo "Test failed for rapids-singlecell"
+          echo "failure_type=test" >> $GITHUB_ENV
+    
+      - name: Check for open failure issue
+        if: failure() && github.event_name == 'schedule'
+        id: find_issue
+        run: |
+          ISSUE_TITLE="Integration Testing CI ${failure_type^} Failure on python rapids_singlecell"
+          echo "Checking for existing issue: $ISSUE_TITLE"
+          ISSUE_COUNT=$(gh issue list --repo scverse/rapids_singlecell --state open --search "${ISSUE_TITLE}" --json number --jq 'length')
+          if [[ "$ISSUE_COUNT" -gt 0 ]]; then
+            echo "${failure_type^} failure issue already exists for today."
+            echo "issue_exists=true" >> $GITHUB_ENV
+          else
+            echo "issue_exists=false" >> $GITHUB_ENV
+            echo "issue_title=$ISSUE_TITLE" >> $GITHUB_ENV
+          fi
+
+      - name: Report failure issue
+        if: failure() && env.issue_exists == 'false' && github.event_name == 'schedule'
+        run: |
+          RUN_URL="${{ github.server_url }}/${{ github.repository }}/actions/runs/${{ github.run_id }}"
+          ISSUE_BODY="The daily CI failed on ${failure_type} for rapids_singlecell failed.  Please go to [the logs of the integration testing repo](${RUN_URL}) to review. @scverse/anndata"
+          gh issue create --repo scverse/rapids_singlecell --title "${{ env.issue_title }}" --body "${ISSUE_BODY}"
+
+
+
+  keepalive-job:
+    name: Keepalive Workflow
+    runs-on: ubuntu-latest
+    permissions:
+      actions: write
+    steps:
+      - name: Re-enable workflow
+        env:
+          GITHUB_TOKEN: ${{ github.token }}
+        shell: sh
+        run: |
+          gh api --verbose -X PUT "repos/${GITHUB_REPOSITORY}/actions/workflows/rsc_integration-test.yml/enable"
\ No newline at end of file
diff --git a/README.md b/README.md
index e30ae62..2da886d 100644
--- a/README.md
+++ b/README.md
@@ -19,6 +19,7 @@ The following packages are tested:
 - scvi-tools
 - pertpy
 - decoupler
+- rapids-singlecell
 
 ## How it Works