diff --git a/backends/qualcomm/__init__.py b/backends/qualcomm/__init__.py
index 5770dfb0fcd..4864340d811 100644
--- a/backends/qualcomm/__init__.py
+++ b/backends/qualcomm/__init__.py
@@ -1,5 +1,8 @@
 import os
 
+import cpuinfo
+import torch
+
 from .scripts.download_qnn_sdk import install_qnn_sdk, is_linux_x86
 
 
@@ -11,3 +14,8 @@
     ok = install_qnn_sdk()
     if not ok:
         raise RuntimeError("Failed to install QNN SDK. Please check the logs above.")
+
+info = cpuinfo.get_cpu_info()
+vendor = info.get("vendor_id_raw", "").lower()
+if "amd" in vendor:
+    torch.backends.mkldnn.enabled = False
diff --git a/backends/qualcomm/scripts/build.sh b/backends/qualcomm/scripts/build.sh
index e3b31a2fe1c..aebbb9bbd6c 100755
--- a/backends/qualcomm/scripts/build.sh
+++ b/backends/qualcomm/scripts/build.sh
@@ -7,6 +7,7 @@
 set -e
 
 pip install pydot
+pip install py-cpuinfo
 
 # Check if running on macOS/Darwin
 if [[ "$(uname -s)" == "Darwin" ]]; then