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DESCRIPTION
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Package: omicScope
Title: A Comprehensive and Integrated Framework for Transcriptomic Data Analysis
Version: 0.0.4
Authors@R:
person("Jun", "Zhang", , "3219030654@stu.cpu.edu.cn", role = c("aut", "cre"))
Description: Provides a streamlined and user-friendly workflow for the end-to-end
analysis of transcriptomic data. 'omicScope' leverages the SummarizedExperiment
class for robust data management and offers a suite of tools for essential analysis
steps, including data normalization, differential expression analysis (interfacing
with popular methods like DESeq2, edgeR, and limma), and advanced functional
interpretation. A key feature is the implementation of pathway and transcription
factor (TF) activity inference using the 'decoupleR' framework, enabling users
to move from gene expression changes to functional biological insights within a
single, cohesive environment..
License: GPL (>= 3)
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Depends: R (>= 4.1.0)
Imports:
clusterProfiler,
ComplexHeatmap,
cowplot,
DESeq2,
dplyr,
edgeR,
GenomicRanges,
ggplot2,
IRanges,
limma,
Matrix,
methods,
Rsubread,
rtracklayer,
S4Vectors,
SummarizedExperiment,
tibble,
tidyr,
corrplot,
scales,
data.table,
magrittr,
Rsamtools,
ggbio,
Signac,
Seurat,
SeuratObject,
GenomeInfoDb
Enhances:
Rtsne,
umap
Suggests:
ggpubr,
decoupleR,
ggpp,
ggrepel,
knitr,
OmnipathR,
rmarkdown,
ggsurvfit,
survival,
maxstat,
ggpubr,
ggh4x,
ggarrow,
ggnewscale
VignetteBuilder: knitr