diff --git a/.changeset/inspect-hotkey-default.md b/.changeset/inspect-hotkey-default.md
new file mode 100644
index 00000000..2d21c3f2
--- /dev/null
+++ b/.changeset/inspect-hotkey-default.md
@@ -0,0 +1,5 @@
+---
+'@tanstack/devtools': patch
+---
+
+Changed default `inspectHotkey` from `["Shift", "CtrlOrMeta"]` to `["Shift", "Alt", "CtrlOrMeta"]` to avoid conflicts with browser shortcuts (Ctrl/Cmd + Shift + Click opens links in new tabs).
diff --git a/packages/devtools/src/context/devtools-store.ts b/packages/devtools/src/context/devtools-store.ts
index 94e20032..5e3b4f0f 100644
--- a/packages/devtools/src/context/devtools-store.ts
+++ b/packages/devtools/src/context/devtools-store.ts
@@ -54,7 +54,7 @@ export type DevtoolsStore = {
     openHotkey: Array<KeyboardKey>
     /**
      * The hotkey to open the source inspector
-     * @default ["Shift", "CtrlOrMeta"]
+     * @default ["Shift", "Alt", "CtrlOrMeta"]
      */
     inspectHotkey: Array<KeyboardKey>
     /**
@@ -100,7 +100,7 @@ export const initialState: DevtoolsStore = {
     position: 'bottom-right',
     panelLocation: 'bottom',
     openHotkey: ['Control', '~'],
-    inspectHotkey: ['Shift', 'CtrlOrMeta'],
+    inspectHotkey: ['Shift', 'Alt', 'CtrlOrMeta'],
     requireUrlFlag: false,
     urlFlag: 'tanstack-devtools',
     theme: