diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index af546b37c81e89..e7f03c9900b3ba 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -29,7 +29,7 @@ cached-ipaddress==1.0.1
 certifi>=2021.5.30
 ciso8601==2.3.3
 cronsim==2.7
-cryptography==48.0.0
+cryptography==50.0.0
 dbus-fast==5.0.3
 file-read-backwards==2.0.0
 fnv-hash-fast==2.0.3