diff --git a/monai/networks/blocks/warp.py b/monai/networks/blocks/warp.py
index ddd3a350d5..a2bfe21c93 100644
--- a/monai/networks/blocks/warp.py
+++ b/monai/networks/blocks/warp.py
@@ -155,7 +155,10 @@ def forward(self, image: torch.Tensor, ddf: torch.Tensor):
 
         if not _use_compiled:  # pytorch native grid_sample
             for i, dim in enumerate(grid.shape[1:-1]):
-                grid[..., i] = grid[..., i] * 2 / (dim - 1) - 1
+                # guard against a singleton spatial dim (e.g. a single-slice volume), where
+                # ``dim - 1 == 0`` would divide by zero; clamp the denominator to 1 so the lone
+                # voxel maps to -1, matching ``monai.networks.utils.normalize_transform``.
+                grid[..., i] = grid[..., i] * 2 / max(dim - 1, 1) - 1
             index_ordering: list[int] = list(range(spatial_dims - 1, -1, -1))
             grid = grid[..., index_ordering]  # z, y, x -> x, y, z
             return F.grid_sample(
diff --git a/tests/networks/blocks/warp/test_warp.py b/tests/networks/blocks/warp/test_warp.py
index 93af559790..6ee4230783 100644
--- a/tests/networks/blocks/warp/test_warp.py
+++ b/tests/networks/blocks/warp/test_warp.py
@@ -12,6 +12,7 @@
 
 import unittest
 from pathlib import Path
+from unittest import mock
 
 import numpy as np
 import torch
@@ -138,6 +139,28 @@ def test_ill_shape(self):
         with self.assertRaisesRegex(ValueError, ""):
             warp_layer(image=torch.arange(4).reshape((1, 1, 2, 2)).to(dtype=torch.float), ddf=torch.zeros(1, 2, 3, 3))
 
+    @mock.patch("monai.networks.blocks.warp.USE_COMPILED", False)
+    def test_singleton_spatial_dim(self):
+        """
+        Regression test for a singleton spatial dimension (a single-slice volume or a
+        single-row/column image), where the grid normalization ``* 2 / (dim - 1)`` previously
+        divided by zero.
+
+        The native ``grid_sample`` path is forced via ``USE_COMPILED=False`` because only that
+        branch normalizes the grid; the csrc ``grid_pull`` path is unaffected. ``padding_mode``
+        is ``"zeros"`` so an out-of-range (pre-fix ``nan``) coordinate maps to 0 and exposes the
+        bug, whereas ``"border"``/``"reflection"`` would clamp onto the lone voxel and mask it.
+        For a zero displacement field the warped output must contain no ``nan`` and must equal
+        the input image.
+        """
+        for shape, ndim in [((1, 1, 1, 4, 4), 3), ((1, 1, 1, 5), 2), ((1, 1, 5, 1), 2)]:
+            image = torch.rand(*shape)
+            ddf = torch.zeros(shape[0], ndim, *shape[2:])
+            warp_layer = Warp(mode="bilinear", padding_mode="zeros")
+            result = warp_layer(image, ddf)
+            self.assertFalse(torch.isnan(result).any(), f"NaN in warp output for shape {shape}")
+            np.testing.assert_allclose(result.cpu().numpy(), image.cpu().numpy(), rtol=1e-4, atol=1e-4)
+
     def test_grad(self):
         for b in GridSampleMode:
             for p in GridSamplePadMode: