@@ -521,6 +521,8 @@ Detailed field description
521521- ``measurement `` [NUMERIC, REQUIRED]
522522
523523 The measured value in the same units/scale as the model output.
524+ If the corresponding ``noiseDistribution `` specifies a discrete distribution,
525+ this value must be integral.
524526
525527- ``time `` [NUMERIC OR ``inf ``, REQUIRED]
526528
@@ -746,11 +748,25 @@ Detailed field description
746748Noise distributions
747749~~~~~~~~~~~~~~~~~~~
748750
749- Denote by :math: `m` the measured value,
751+ The supported continuous and discrete probability distributions to model
752+ measurement noise are listed below.
753+ Those distributions are for a single data point.
754+ For a collection :math: `D=\{ m_i\} _i` of data points and corresponding
755+ simulations :math: `Y=\{ y_i\} _i`
756+ and noise parameters :math: `\Sigma =\{\sigma _i\} _i`,
757+ the current specification assumes independence, i.e. the full distribution is
758+
759+ .. math ::
760+ \pi (D|Y,\Sigma ) = \prod _i\pi (m_i|y_i,\sigma _i)
761+
762+ Continuous distributions
763+ ++++++++++++++++++++++++
764+
765+ Denote by :math: `m:=\text {measurement}` the measured value,
750766:math: `y:=\text {observableFormula}` the simulated value
751767(the location parameter of the noise distribution),
752- and :math: `\sigma ` the scale parameter of the noise distribution
753- as given via the `` noiseFormula `` field ( the standard deviation of a normal,
768+ and :math: `\sigma := \text {noiseFormula} ` the scale parameter of the noise
769+ distribution (e.g., the standard deviation of a normal,
754770or the scale parameter of a Laplace model).
755771Then we have the following effective noise distributions:
756772
@@ -780,14 +796,46 @@ Then we have the following effective noise distributions:
780796 - .. math::
781797 \pi(m|y,\sigma) = \frac{1}{2\sigma m}\exp\left(-\frac{|\log m - \log y|}{\sigma}\right)
782798
783- The distributions above are for a single data point.
784- For a collection :math: `D=\{ m_i\} _i` of data points and corresponding
785- simulations :math: `Y=\{ y_i\} _i`
786- and noise parameters :math: `\Sigma =\{\sigma _i\} _i`,
787- the current specification assumes independence, i.e. the full distribution is
799+ Discrete distributions
800+ ++++++++++++++++++++++
788801
789- .. math ::
790- \pi (D|Y,\Sigma ) = \prod _i\pi (m_i|y_i,\sigma _i)
802+ Denote by :math: `m` the ``measurement `` in the measurement table,
803+ then we have the following effective noise distributions:
804+
805+ .. list-table ::
806+ :header-rows: 1
807+ :widths: 10 10 80
808+
809+ * - Type
810+ - ``noiseDistribution ``
811+ - Probability density function (PDF)
812+ * - Poisson distribution
813+ - ``poisson ``
814+ - .. math::
815+ \pi(m|\lambda) = \frac{\lambda^m\exp(-\lambda)}{m!}
816+
817+ where the rate :math:`\lambda` is given via ``observableFormula``.
818+ ``noiseFormula`` must be empty in this case.
819+ The measurement :math:`m` is the number of observed events
820+ and must be a non-negative integer.
821+ * - Binomial distribution
822+ - ``binomial ``
823+ - .. math::
824+ \pi(m|n,p) = \binom{n}{m}p^m(1-p)^{n-m}
825+
826+ where :math:`n` is the number of trials given via ``observableFormula``
827+ and :math:`p` the probability of success given via ``noiseFormula``.
828+ The measurement :math:`m` is the number of observed successes
829+ and must be an integer between 0 and :math:`n`.
830+ * - Negative binomial distribution
831+ - ``negative-binomial ``
832+ - .. math::
833+ \pi(m|r,p) = \binom{m+r-1}{m}p^r(1-p)^m
834+
835+ where :math:`r` is the number of successes given via ``observableFormula``
836+ and :math:`p` the probability of success given via ``noiseFormula``.
837+ The measurement :math:`m` is the number of observed failures
838+ and must be a non-negative integer.
791839
792840.. _v2_parameter_table :
793841
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