diff --git a/.github/workflows/arm.yml b/.github/workflows/arm.yml
index 6210c6def8d..4998b69090b 100644
--- a/.github/workflows/arm.yml
+++ b/.github/workflows/arm.yml
@@ -54,31 +54,6 @@ jobs:
               ITK_USE_CLANG_FORMAT:BOOL=OFF
             ctest-options: ""
 
-          - os: macos-15
-            name: "x86_64-rosetta"
-            cmake-build-type: "Release"
-            cmake-generator: "Ninja"
-            python-version: ""
-            ctest-cache: |
-              BUILD_SHARED_LIBS:BOOL=OFF
-              BUILD_EXAMPLES:BOOL=OFF
-              ITK_WRAP_PYTHON:BOOL=OFF
-              ITK_USE_CLANG_FORMAT:BOOL=OFF
-              CMAKE_OSX_ARCHITECTURES:STRING=x86_64
-            ctest-options: ""
-
-          - os: macos-15
-            name: "Python"
-            cmake-build-type: "Release"
-            cmake-generator: "Ninja"
-            python-version: "3.11"
-            ctest-cache: |
-              BUILD_SHARED_LIBS:BOOL=OFF
-              BUILD_EXAMPLES:BOOL=OFF
-              ITK_WRAP_PYTHON:BOOL=ON
-              ITK_USE_CLANG_FORMAT:BOOL=OFF
-            ctest-options: "-E itkPyBufferMemoryLeakTest"
-
     name: ARMBUILD-${{ matrix.name }}
 
     steps:
@@ -94,9 +69,8 @@ jobs:
           echo "CCACHE_BASEDIR=${GITHUB_WORKSPACE}" >> "$GITHUB_ENV"
           echo "CCACHE_COMPILERCHECK=content" >> "$GITHUB_ENV"
           echo "CCACHE_NOHASHDIR=true" >> "$GITHUB_ENV"
-          echo "CCACHE_NODIRECT=1" >> "$GITHUB_ENV"
           echo "CCACHE_DIR=${{ runner.temp }}/ccache" >> "$GITHUB_ENV"
-          echo "CCACHE_MAXSIZE=2.4G" >> "$GITHUB_ENV"
+          echo "CCACHE_MAXSIZE=5G" >> "$GITHUB_ENV"
           if [ "$RUNNER_OS" == "Linux" ]; then
             sudo apt-get update -qq && sudo apt-get install -y ccache locales
             sudo locale-gen de_DE.UTF-8
@@ -109,7 +83,11 @@ jobs:
         uses: actions/cache/restore@v5
         with:
           path: ${{ runner.temp }}/ccache
-          key: ccache-v1-${{ matrix.os }}-${{ matrix.name }}
+          key: >-
+            ccache-v3-${{ runner.os }}-${{ matrix.name }}-${{ hashFiles('CMakeLists.txt', 'cmake/**', '**/*.cmake', '**/pyproject.toml', '**/pixi.lock') }}
+          restore-keys: |
+            ccache-v3-${{ runner.os }}-${{ matrix.name }}-
+            ccache-v3-${{ runner.os }}-
 
       - name: Show ccache configuration, stats and maintenance
         shell: bash
@@ -170,11 +148,12 @@ jobs:
         env:
           CTEST_OUTPUT_ON_FAILURE: 1
       - name: Save compiler cache
-        if: github.ref == 'refs/heads/main'
+        if: always()
         uses: actions/cache/save@v5
         with:
           path: ${{ runner.temp }}/ccache
-          key: ccache-v1-${{ matrix.os }}-${{ matrix.name }}
+          key: >-
+            ccache-v3-${{ runner.os }}-${{ matrix.name }}-${{ hashFiles('CMakeLists.txt', 'cmake/**', '**/*.cmake', '**/pyproject.toml', '**/pixi.lock') }}
 
       - name: ccache stats
         if: always()
diff --git a/.github/workflows/pixi.yml b/.github/workflows/pixi.yml
index df848955b49..51075a8d72f 100644
--- a/.github/workflows/pixi.yml
+++ b/.github/workflows/pixi.yml
@@ -14,16 +14,17 @@ on:
             - 'Utilities/ITKv5Preparation/**'
             - 'Utilities/Maintenance/**'
             - 'Modules/Remote/*.remote.cmake'
-    pull_request:
-        paths-ignore:
-            - '*.md'
-            - LICENSE
-            - NOTICE
-            - 'Documentation/**'
-            - 'Utilities/Debugger/**'
-            - 'Utilities/ITKv5Preparation/**'
-            - 'Utilities/Maintenance/**'
-            - 'Modules/Remote/*.remote.cmake'
+    # WIP: PR trigger disabled to isolate ARMBUILD-Ubuntu-24.04-arm CI
+    # pull_request:
+    #     paths-ignore:
+    #         - '*.md'
+    #         - LICENSE
+    #         - NOTICE
+    #         - 'Documentation/**'
+    #         - 'Utilities/Debugger/**'
+    #         - 'Utilities/ITKv5Preparation/**'
+    #         - 'Utilities/Maintenance/**'
+    #         - 'Modules/Remote/*.remote.cmake'
 
 concurrency:
   group: '${{ github.workflow }}@${{ github.head_ref || github.ref }}'
@@ -53,9 +54,8 @@ jobs:
             echo "CCACHE_BASEDIR=${GITHUB_WORKSPACE}" >> "$GITHUB_ENV"
             echo "CCACHE_COMPILERCHECK=content" >> "$GITHUB_ENV"
             echo "CCACHE_NOHASHDIR=true" >> "$GITHUB_ENV"
-            echo "CCACHE_NODIRECT=1" >> "$GITHUB_ENV"
             echo "CCACHE_DIR=${{ runner.temp }}/ccache" >> "$GITHUB_ENV"
-            echo "CCACHE_MAXSIZE=2.4G" >> "$GITHUB_ENV"
+            echo "CCACHE_MAXSIZE=5G" >> "$GITHUB_ENV"
             if [ "$RUNNER_OS" == "Linux" ]; then
               sudo apt-get update -qq && sudo apt-get install -y ccache locales
               sudo locale-gen de_DE.UTF-8
@@ -70,7 +70,11 @@ jobs:
           uses: actions/cache/restore@v5
           with:
             path: ${{ runner.temp }}/ccache
-            key: ccache-v1-${{ matrix.os }}-pixi-cxx
+            key: >-
+              ccache-v3-${{ runner.os }}-pixi-cxx-${{ hashFiles('CMakeLists.txt', 'cmake/**', '**/*.cmake', '**/pyproject.toml', '**/pixi.lock') }}
+            restore-keys: |
+              ccache-v3-${{ runner.os }}-pixi-cxx-
+              ccache-v3-${{ runner.os }}-
 
         - name: Show ccache configuration, stats and maintenance
           shell: bash
@@ -150,11 +154,12 @@ jobs:
             echo "****** df -h /"
             df -h /
         - name: Save compiler cache
-          if: github.ref == 'refs/heads/main'
+          if: always()
           uses: actions/cache/save@v5
           with:
             path: ${{ runner.temp }}/ccache
-            key: ccache-v1-${{ matrix.os }}-pixi-cxx
+            key: >-
+              ccache-v3-${{ runner.os }}-pixi-cxx-${{ hashFiles('CMakeLists.txt', 'cmake/**', '**/*.cmake', '**/pyproject.toml', '**/pixi.lock') }}
 
         - name: ccache stats
           if: always()
diff --git a/Modules/ThirdParty/Eigen3/src/itkeigen/Eigen/src/Core/products/SelfadjointMatrixVector.h b/Modules/ThirdParty/Eigen3/src/itkeigen/Eigen/src/Core/products/SelfadjointMatrixVector.h
index f7387601ffb..1b74a1d24fe 100644
--- a/Modules/ThirdParty/Eigen3/src/itkeigen/Eigen/src/Core/products/SelfadjointMatrixVector.h
+++ b/Modules/ThirdParty/Eigen3/src/itkeigen/Eigen/src/Core/products/SelfadjointMatrixVector.h
@@ -13,6 +13,13 @@
 // IWYU pragma: private
 #include "../InternalHeaderCheck.h"
 
+// GCC on ARM (aarch64) emits false-positive -Wmaybe-uninitialized warnings
+// in the vectorized selfadjoint matrix-vector product kernel.
+#if defined(__GNUC__) && !defined(__clang__)
+#  pragma GCC diagnostic push
+#  pragma GCC diagnostic ignored "-Wmaybe-uninitialized"
+#endif
+
 namespace Eigen {
 
 namespace internal {
@@ -250,4 +257,8 @@ struct selfadjoint_product_impl<Lhs, 0, true, Rhs, RhsMode, false> {
 
 }  // end namespace Eigen
 
+#if defined(__GNUC__) && !defined(__clang__)
+#  pragma GCC diagnostic pop
+#endif
+
 #endif  // EIGEN_SELFADJOINT_MATRIX_VECTOR_H
diff --git a/Testing/ContinuousIntegration/AzurePipelinesLinux.yml b/Testing/ContinuousIntegration/AzurePipelinesLinux.yml
index 0c8a107a95d..3dd3829ee54 100644
--- a/Testing/ContinuousIntegration/AzurePipelinesLinux.yml
+++ b/Testing/ContinuousIntegration/AzurePipelinesLinux.yml
@@ -15,17 +15,8 @@ trigger:
     - Utilities/ITKv5Preparation/*
     - Utilities/Maintenance/*
     - Modules/Remote/*.remote.cmake
-pr:
-  paths:
-    exclude:
-    - '*.md'
-    - LICENSE
-    - NOTICE
-    - Documentation/*
-    - Utilities/Debugger/*
-    - Utilities/ITKv5Preparation/*
-    - Utilities/Maintenance/*
-    - Modules/Remote/*.remote.cmake
+# WIP: PR trigger disabled to isolate ARMBUILD-Ubuntu-24.04-arm CI
+pr: none
 variables:
   ExternalDataVersion: 5.4.5
   CCACHE_DIR: $(Pipeline.Workspace)/.ccache
diff --git a/Testing/ContinuousIntegration/AzurePipelinesLinuxPython.yml b/Testing/ContinuousIntegration/AzurePipelinesLinuxPython.yml
index 1e8bfa75917..e2b89fb5685 100644
--- a/Testing/ContinuousIntegration/AzurePipelinesLinuxPython.yml
+++ b/Testing/ContinuousIntegration/AzurePipelinesLinuxPython.yml
@@ -15,17 +15,8 @@ trigger:
     - Utilities/ITKv5Preparation/*
     - Utilities/Maintenance/*
     - Modules/Remote/*.remote.cmake
-pr:
-  paths:
-    exclude:
-    - '*.md'
-    - LICENSE
-    - NOTICE
-    - Documentation/*
-    - Utilities/Debugger/*
-    - Utilities/ITKv5Preparation/*
-    - Utilities/Maintenance/*
-    - Modules/Remote/*.remote.cmake
+# WIP: PR trigger disabled to isolate ARMBUILD-Ubuntu-24.04-arm CI
+pr: none
 variables:
   ExternalDataVersion: 5.4.5
   CCACHE_DIR: $(Pipeline.Workspace)/.ccache
diff --git a/Testing/ContinuousIntegration/AzurePipelinesMacOS.yml b/Testing/ContinuousIntegration/AzurePipelinesMacOS.yml
index e90d7ea177c..0bcc41fd6e1 100644
--- a/Testing/ContinuousIntegration/AzurePipelinesMacOS.yml
+++ b/Testing/ContinuousIntegration/AzurePipelinesMacOS.yml
@@ -15,17 +15,8 @@ trigger:
     - Utilities/ITKv5Preparation/*
     - Utilities/Maintenance/*
     - Modules/Remote/*.remote.cmake
-pr:
-  paths:
-    exclude:
-    - '*.md'
-    - LICENSE
-    - NOTICE
-    - Documentation/*
-    - Utilities/Debugger/*
-    - Utilities/ITKv5Preparation/*
-    - Utilities/Maintenance/*
-    - Modules/Remote/*.remote.cmake
+# WIP: PR trigger disabled to isolate ARMBUILD-Ubuntu-24.04-arm CI
+pr: none
 variables:
   ExternalDataVersion: 5.4.5
   CCACHE_DIR: $(Pipeline.Workspace)/.ccache
diff --git a/Testing/ContinuousIntegration/AzurePipelinesMacOSPython.yml b/Testing/ContinuousIntegration/AzurePipelinesMacOSPython.yml
index 26d5744259e..15ce311fb80 100644
--- a/Testing/ContinuousIntegration/AzurePipelinesMacOSPython.yml
+++ b/Testing/ContinuousIntegration/AzurePipelinesMacOSPython.yml
@@ -15,17 +15,8 @@ trigger:
     - Utilities/ITKv5Preparation/*
     - Utilities/Maintenance/*
     - Modules/Remote/*.remote.cmake
-pr:
-  paths:
-    exclude:
-    - '*.md'
-    - LICENSE
-    - NOTICE
-    - Documentation/*
-    - Utilities/Debugger/*
-    - Utilities/ITKv5Preparation/*
-    - Utilities/Maintenance/*
-    - Modules/Remote/*.remote.cmake
+# WIP: PR trigger disabled to isolate ARMBUILD-Ubuntu-24.04-arm CI
+pr: none
 variables:
   ExternalDataVersion: 5.4.5
   CCACHE_DIR: $(Pipeline.Workspace)/.ccache
diff --git a/Testing/ContinuousIntegration/AzurePipelinesWindows.yml b/Testing/ContinuousIntegration/AzurePipelinesWindows.yml
index 039219ea2df..869ad50b128 100644
--- a/Testing/ContinuousIntegration/AzurePipelinesWindows.yml
+++ b/Testing/ContinuousIntegration/AzurePipelinesWindows.yml
@@ -15,17 +15,8 @@ trigger:
     - Utilities/ITKv5Preparation/*
     - Utilities/Maintenance/*
     - Modules/Remote/*.remote.cmake
-pr:
-  paths:
-    exclude:
-    - '*.md'
-    - LICENSE
-    - NOTICE
-    - Documentation/*
-    - Utilities/Debugger/*
-    - Utilities/ITKv5Preparation/*
-    - Utilities/Maintenance/*
-    - Modules/Remote/*.remote.cmake
+# WIP: PR trigger disabled to isolate ARMBUILD-Ubuntu-24.04-arm CI
+pr: none
 variables:
   ExternalDataVersion: 5.4.5
   CCACHE_DIR: $(Pipeline.Workspace)/.ccache
diff --git a/Testing/ContinuousIntegration/AzurePipelinesWindowsPython.yml b/Testing/ContinuousIntegration/AzurePipelinesWindowsPython.yml
index 16e26f9fbeb..e5669466c12 100644
--- a/Testing/ContinuousIntegration/AzurePipelinesWindowsPython.yml
+++ b/Testing/ContinuousIntegration/AzurePipelinesWindowsPython.yml
@@ -15,17 +15,8 @@ trigger:
     - Utilities/ITKv5Preparation/*
     - Utilities/Maintenance/*
     - Modules/Remote/*.remote.cmake
-pr:
-  paths:
-    exclude:
-    - '*.md'
-    - LICENSE
-    - NOTICE
-    - Documentation/*
-    - Utilities/Debugger/*
-    - Utilities/ITKv5Preparation/*
-    - Utilities/Maintenance/*
-    - Modules/Remote/*.remote.cmake
+# WIP: PR trigger disabled to isolate ARMBUILD-Ubuntu-24.04-arm CI
+pr: none
 variables:
   ExternalDataVersion: 5.4.5
   CCACHE_DIR: $(Pipeline.Workspace)/.ccache