diff --git a/pyproject.toml b/pyproject.toml
index ca2c739a..f289867c 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -31,7 +31,7 @@ datadog = ">=0.51.0,<1.0.0"
 wrapt = "^1.11.2"
 ddtrace = [
     {version = ">=3.19.1,<4", python = ">=3.8,<3.10"},
-    {version = ">=4.1.1,<5", python = ">=3.10"}
+    {version = ">=4.1.1,<5,!=4.6.*", python = ">=3.10"}
 ]
 ujson = ">=5.9.0"
 botocore = { version = "^1.34.0", optional = true }